2-Phenyl-5,7-bis(prop-2-en-1-yloxy)-4H-chromen-4-one
نویسندگان
چکیده
In the title compound, C(21)H(18)O(4), tthe dihedral angle between the chromene ring system and the pendant phenyl ring is 6.1 (1)°. The crystal structure is stabilized by an intermolecular C-H⋯O and C-H⋯π inter-actions.
منابع مشابه
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In order to develop new selective COX-2 inhibitors, a new series of 2-phenyl-4H-chromen-4-one derivatives possessing a methylsulfonyl pharmacophore group at the para position of the C-4 phenyl ring were designed, synthesized, and evaluated for cyclooxygenase-2 inhibitory activity. In vitro COX-1/COX-2 isozyme inhibition structure-activity studies identified 3-(benzyloxy)-2-[4-(methylsulfonyl)ph...
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In the title compound, C(29)H(22)O(4), the chromene ring is almost planar with a small puckering [0.143 (2) Å]. The crystal structure is stabilized by C-H⋯O and C-H⋯π inter-actions. Edge-to-face (centroid-centroid distances of 3.894 and 3.673 Å) and face-to-face (centroid-centroid distance of 3.460 Å) π-π-ring electron inter-actions are also observed.
متن کامل2-(4-Chlorophenyl)chromen-4-one
The title compound, C(15)H(9)ClO(2), is a synthetic flavonoid obtained by the cyclization of 3-(4-chloro-phen-yl)-1-(2-hy-droxy-phen-yl)prop-2-en-1-one. The 4-chloro-phenyl ring is twisted at an angle of 11.54° with respect to the chromen-4-one skeleton. In the crystal, pairs of mol-ecules are inter-connected by weak Cl⋯Cl inter-actions [3.3089 (10) Å] forming dimmers which are further peripher...
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The asymmetric unit of the title compound, C(17)H(14)O(4), contains two independent mol-ecules which differ in the relative orientations of the phenyl rings with repect to the essentially planar [maximum deviations of 0.029 (2) and 0.050 (2) Å in the two mol-ecules] chromene fused-ring system, forming dihedral angles of 10.3 (5) and 30.86 (5)° in the two mol-ecules. The crystal structure is sta...
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